Hepac is a leading Dutch producer of high quality, fully traceable crude porcine heparin.

Hepac has solid access to high quality mucosa from European origin. Together with robust processes, state of the art process equipment and stringent quality control Hepac is a trusted partner for international customers. Hepac is part of Darling Ingredients.

What is heparin?

Heparin is one of the oldest drugs currently in widespread clinical use. It was originally isolated from canine liver cells, hence its name (hepar or "ήπαρ" is Greek for "liver"; hepar + -in). Heparin was discovered by Jay McLean and William Henry Howell in 1916.

Heparin prevents the blood from clotting and is used to treat and prevent deep vein thrombosis and pulmonary embolism. It is also used as part of the treatment of myocardial infarction and unstable angina. Another application of heparin is an inner surface anticoagulant on various experimental and medical devices such as test tubes and renal dialysis machines.

Although heparin can be synthesized by means of chemical processes, most of the worldwide produced heparin is extracted from animal tissue, porcine intestinal mucosa specifically. The production of heparin is located near the source of raw material. Area’s like China, North America and Europa are the main pork producing areas and these are also the locations of the main heparin producers.

Heparin’s main source, porcine intestinal mucosa, is a by-product of pork slaughtering and is released while cleaning the pork’s casing. Cleaning casings is a specialized process that requires highly skilled staff and state of the art equipment. To avoid degradation of the heparin content and decay, stabilizing agent is added directly after harvesting. The material is stored in bulk tanks awaiting transport to the processing facility.